What Is Glabridin?
Glabridin is a prenylated isoflavan from Glycyrrhiza glabra (光果甘草) root and rhizome. Brands buy it as a HPLC-standardized marker—not as generic “licorice extract”—for beauty, antioxidant, and healthy aging formulas.
| Parameter | Detail |
|---|---|
| CAS | 59870-68-7 |
| Formula / MW | C₂₀H₂₀O₄ · 324.37 |
| Source | Glycyrrhiza glabra root & rhizome |
| Natural abundance | Typically ~0.1%–0.3% in root material (high-purity supply is yield-intensive) |
| Appearance | Brown (typical 10%) to white (90% / 95% / 98% / water-soluble 10%) |
| Key handling trait | Lipophilic / poor native water solubility — unless using water-soluble grade |
Do not confuse with glycyrrhizin. Different compound, different purchasing and regulatory considerations. Full comparison: Glabridin vs Glycyrrhizin.
Why Brands Choose Glabridin
Glabridin demand is rising because beauty and healthy aging buyers want a differentiated botanical polyphenol with assay-backed storytelling—not another vitamin-only SKU.
Primary application lanes
| Application | Typical positioning | Common formats |
|---|---|---|
| Beauty from within | Radiance/beauty polyphenol support (compliant wording) | Capsules, softgel |
| Healthy Aging | Antioxidant/polyphenol nutrition | Softgel, capsule |
| Women’s beauty wellness | Botanical beauty routines | Capsules, powder, stick packs |
| Aqueous/convenience formats | Water-dispersible beauty concepts | Stick packs, powder, selected gummies |
Popular stacks: Glabridin + Vitamin C + Ceramide · Glabridin + Astaxanthin · Glabridin + CoQ10 / Resveratrol · Glabridin + Collagen / HA (often split SKUs)
Continue to finished-product OEM: Beauty Supplements · Astaxanthin
Ingredient Specifications
Ask for batch COA against specification—not a marketing PDF.
Commercial grades
| Product | Assay (HPLC) | Appearance | Best starting use |
|---|---|---|---|
| Glabridin | 10% | Brown | Entry / multi-ingredient capsules |
| Glabridin | 90% | White | Softgels & high-marker beauty stacks |
| Glabridin | 95% | White | Premium / near-isolate positioning |
| Glabridin | 98% | White | Max purity / tight fill-weight systems |
| Supramolecular Glabridin (Water-Soluble) | 10% | White | Drink powders, stick packs, aqueous concepts |
Custom mid-assay OEM grades available on request.
Which grade should you choose?
| If you need… | Start with |
|---|---|
| Cost-effective beauty capsule | 10% |
| Softgel / low fill weight / high-marker story | 90% / 95% / 98% |
| Aqueous powder, stick pack, or water-rich matrix | Water-soluble 10% |
Deep dive (cost-in-use, fill weight, when 98% wins): Glabridin 10% vs 90% vs 98%.
QC Framework
| Parameter | Typical target |
|---|---|
| Identification / Assay | HPLC |
| LOD | Typically ≤5.0% (confirm per grade) |
| Heavy metals | Pb, As, Cd, Hg per market limits |
| Microbiology | Per specification |
| Residual solvents | ICH Q3C / buyer limits |
| Storage | Cool, dry, light- & oxygen-protected |
| Shelf life | Commonly 24 months unopened (confirm per lot) |
[Request Specification Package] · [Request COA] · [Request Water-Soluble Sample]
Keep this section decision-oriented. Full engineering detail lives in the formulation guide.
Format quick map
| Format | Preferred grade family | Watch-out |
|---|---|---|
| Capsule | 10% or 90%+ | Fill budget vs assay |
| Softgel | 90% / 95% / 98% | Oil carrier + antioxidant system |
| Stick pack / drink powder | Water-soluble 10% | Do not force lipophilic 10% into water |
| Gummy | Water-soluble / protected grades | Heat + moisture = engineering project |
Common companions: Vitamin C · Ceramide · Astaxanthin · CoQ10 · Resveratrol · Collagen · Hyaluronic acid · Lycopene · Grape seed · Pine bark
R&D rules of thumb
- Standard glabridin is lipophilic—choose softgel/oil systems or upgrade to water-soluble for aqueous SKUs.
- Protect from heat, light, and oxygen in process and packaging.
- Keep water-soluble 10% as a separate BOM/SKU from standard 10%.
Full guide (solubility, stability, delivery systems, process tips): Glabridin Formulation Guide.
| What buyers receive / should require | Status |
|---|---|
| Batch COA + HPLC assay | ✓ |
| Spec sheet / TDS | ✓ |
| Heavy metals · microbiology · residual solvents | ✓ |
| Third-party testing pathway | Available on request |
| Stability / packaging guidance | Project-based |
| Halal / Kosher / Non-GMO statements | As requested |
KS Nutripharma quality posture: FDA-registered · cGMP · ISO 22000 · HACCP · FSSC 22000 · Halal · Kosher · Non-GMO options
Supplier shortlist checklist: How to Choose a Glabridin Supplier.
KS Nutripharma is not only a drum supplier. After grade approval, we can manufacture finished beauty and healthy aging SKUs.
| Capability | Detail |
|---|---|
| Pathways | Private Label · OEM · ODM |
| Formats | Capsules · softgels · powders · stick packs · gummies (engineering-first) |
| Ingredient pack | 1 kg bags · aluminum foil packs · 25 kg drums |
| Typical finished MOQ bands | Capsules often from ~5,000 units · gummies/softgels commonly from ~10,000 units / SKU (confirm per project) |
| Sampling | Often 7–15 days depending on grade/stock |
| Markets | 60+ export markets with documentation support |
Typical project pattern: grade recommendation → sample/COA → pilot formula → commercial production → export pack
Related hub: Beauty Supplements Contract Manufacturing
Ready to Source Glabridin—or Launch the Finished SKU?
Share a short brief and we will recommend grade, format, and next sampling step:
- Target grade (or ask us to recommend)
- Dosage form
- Target market(s)
- Companion ingredients
- Target mg active / serving + volume
KS Nutripharma — Glabridin Ingredient Manufacturer & Beauty Supplement OEM Partner
Related Resources
Ingredient/solution pages
Supporting Blogs
- What Is Glabridin?
- Glabridin 10% vs 90% vs 98%: Which Grade Should You Buy?
- How to Choose a Glabridin Supplier
- Glabridin Formulation Guide
- Glabridin vs Glycyrrhizin
- Glabridin vs Hydroquinone
- Water-Soluble vs Oil-Soluble Glabridin
- Oral vs Topical Skin Brightening Ingredients
10% · 90% · 95% · 98%, plus Supramolecular / Water-Soluble Glabridin 10%. Custom mid-assay grades on request.
Yes—batch COA, specification package, and sample support are standard pre-PO steps.
No. It is a separate delivery-upgraded SKU for aqueous systems. Do not substitute blindly.
Yes—private label, OEM, and ODM under confidentiality as agreed.
Yes. Capsule/softgel-first beauty launches are a common path, with MOQ-aware scale-up.
Ingredient: sample packs to 25 kg drums. Finished goods: format-dependent. Sampling often 7–15 days; production timelines depend on form, pack, and documentation.
We support documentation packages and destination-market readiness discussions. Final compliance ownership remains with the brand marketer—rules differ by country.
Project-based accelerated/real-time scoping for finished products is available; ingredient storage guidance ships with documentation.
