20-Hydroxyecdysone Bulk Ingredient Supplier for Dietary Supplements
KS Nutripharma® supplies beta-ecdysterone powder (20-hydroxyecdysone, CAS 5289-74-7) from Cyanotis arachnoidea extract for bulk ingredient procurement, supplement development and sports nutrition applications. Available standardized grades include 50%, 60%, 95%, 98% and 99% HPLC, with 90% and 95% UV grades available for specified applications. Batch-specific COA and specification-based QC documentation are available for supplier qualification.
Buyer Specification Snapshot
| Parameter | Commercial Specifications |
| Ingredient | Beta-Ecdysterone |
| Synonym | 20-Hydroxyecdysone |
| CAS Number | 5289-74-7 |
| Molecular Formula | C₂₇H₄₄O₇ |
| Chemical Class | Ecdysteroid |
| Botanical Source | Cyanotis arachnoidea C.B.Clarke |
| Extract Type | Standardized botanical extract |
| Primary HPLC Grades | 50%, 60%, 95%, 98%, 99% |
| UV Grades | 90% / 95% |
| Appearance | Light yellow to off-white powder (higher HPLC grades); brown-yellow powder (other grades) |
| Particle Size | 80 mesh |
| Assay Method | HPLC or UV according to specification |
| COA | Batch-specific |
| Shelf Life | 24 months, subject to approved storage specification |
| Packaging | Confirm by quotation |
| MOQ | Project / volume dependent |
The commercially relevant plant part and extraction details should be confirmed per the approved raw-material specification and accompanying COA.
Available Extract Grades
The extract is supplied in multiple standardized grades. Grade selection should be based on the target beta-ecdysterone assay, analytical method, physical properties, intended application, destination-market requirements and commercial quantity.
| Grade | Assay Method | Assay | Appearance | Mesh | Typical Application |
| Standardized Extract | HPLC | 99% | Light yellow to off-white powder | 80 mesh | High-purity supplement and sports nutrition applications |
| Standardized Extract | HPLC | 98% | Light yellow to off-white powder | 80 mesh | Sports nutrition, dietary supplement development |
| Standardized Extract | HPLC | 95% | Light yellow to off-white powder | 80 mesh | Sports nutrition, dietary supplement development |
| Standardized Extract | HPLC | 60% | Light yellow to off-white powder | 80 mesh | Specified applications |
| Standardized Extract | HPLC | 50% | Brown-yellow powder | 80 mesh | Specified applications |
| Standardized Extract | UV | 90% / 95% | Brown-yellow powder | 80 mesh | Specified applications |
*Application suitability depends on the actual raw-material specification, regulatory requirements and intended market. Not every listed grade should be assumed to be suitable for human dietary supplements.
Available HPLC-standardized grades include 50%, 60%, 95%, 98% and 99%, subject to approved specification and batch availability. The appropriate grade for supplement use should be determined according to the finished-product formula, destination-market requirements and applicable regulatory criteria.
HPLC vs. UV: How Assay Results Should Be Interpreted
Assay percentages should always be interpreted together with the analytical method and specification. HPLC and UV results are method-specific and should not be treated as directly equivalent percentages.
HPLC can provide compound-specific quantification when the analytical procedure is appropriately validated against a beta-ecdysterone reference standard. UV spectrophotometric results, by comparison, depend on the specified analytical procedure, reference basis and reporting conditions.
Documented Batch Examples
The following results are documented examples of assay reporting and are provided to illustrate method-specific interpretation. They are not a guarantee of a fixed assay result for every commercial batch.
| Reported Result | Method | Specification | Status |
|---|---|---|---|
| 98.27% | HPLC | ≥98.00% | Pass |
| 90.52% | UV | ≥90.00% | Pass |
What This Means for Brands
Do not compare “98% HPLC” and “90% UV” as if they were directly equivalent measures of the same analytical quantity. First confirm the assay method, reference basis and acceptance specification shown on the applicable COA.
At KS Nutripharma, beta-ecdysterone grade selection and supplier qualification are based on the approved specification and applicable analytical method—not the headline assay percentage alone. Batch-specific COA documentation is available for qualification.
How to Choose the Right Beta-Ecdysterone Grade for Your Final Projects?
Grade Selection for Procurement
The right beta-ecdysterone grade depends on how the ingredient will be formulated, dosed, costed and qualified—not simply on choosing the highest assay.
KS Nutripharma supplies standardized 50%, 60%, 95%, 98% and 99% HPLC grades, with specified UV grades available for applicable requirements. Grade selection should be agreed during raw-material qualification based on the target active load, dosage form, inclusion weight, analytical requirements and destination-market documentation.
| Procurement Requirement | Grade Selection Consideration |
|---|---|
| Lower cost per active unit | Compare ingredient cost against the actual beta-ecdysterone content rather than comparing price per kg alone. |
| Higher active concentration | 95–99% HPLC grades may reduce the required inclusion weight when the formula is designed around a defined active load. |
| Low inclusion weight | A higher-assay grade may be considered when capsule, tablet or sachet fill weight is constrained. |
| Formula-specific dosage requirement | Select the grade based on the target active amount per serving and the resulting inclusion rate. |
| Physical processing requirements | Confirm color, bulk density, flowability and other relevant physical properties against the approved specification and representative COA. |
| Required analytical basis | Select the grade and assay method required by the approved raw-material specification. |
| Destination-market requirements | Confirm applicable documentation, specifications and testing requirements before commercial qualification. |
What This Means in Practice
Higher assay does not automatically mean a better commercial choice. A higher-purity grade may reduce inclusion weight, but the appropriate grade should also be evaluated against formula requirements, physical handling, analytical specifications and cost per active unit.
Higher-assay grades may exhibit different physical characteristics, including color, bulk density and flowability. These properties should be evaluated using a representative sample and confirmed against the approved specification and COA before commercial qualification.
How KS Nutripharma Supports Grade Selection
KS Nutripharma can scope the appropriate beta-ecdysterone grade based on your target active load, dosage form, inclusion weight and analytical requirements before quotation. Rather than defaulting to the highest assay, we can compare suitable grades against the intended specification and commercial volume.
Send your target dosage, required assay and estimated order volume → Request a Grade & COA Review
The numerical assay value alone is not sufficient when comparing beta-ecdysterone suppliers. Buyers should evaluate the material, analytical basis and batch documentation together before approving a commercial source.
| Qualification Check | What Buyers Should Verify | KS Nutripharma Qualification Support |
|---|---|---|
| Botanical Identity | Confirm the declared botanical source and ingredient identity. | Product specification identifies the applicable botanical source and beta-ecdysterone identity. |
| Actual Assay | Review the actual batch result, not only the advertised grade. | Batch-specific COA available for qualification. |
| Analytical Method | Confirm HPLC or UV and the applicable analytical basis. | Applicable assay method is defined in the approved specification. |
| Specifications | Confirm the minimum acceptance value and agreed QC requirements. | Commercial material is supplied against an approved raw-material specification. |
| COA & Traceability | Verify batch number, actual results and lot traceability. | Batch-specific documentation supports commercial-batch qualification. |
| Contaminant / Microbial Requirements | Confirm applicable heavy-metal, pesticide, residual-solvent and microbiological requirements. | QC requirements are defined according to the approved specification and destination-market requirements. |
| Sample vs. Commercial Batch | Confirm that the qualified sample and documentation are representative of the intended commercial supply. | Sample → qualification → bulk supply pathway. |
| Repeat Supply | Confirm that the approved specification can be maintained for subsequent orders. | Specification-based production and repeat bulk supply support. |
Why This Matters
For beta-ecdysterone procurement, KS Nutripharma does not position assay percentage alone as the basis for supplier selection. We focus on the combination of assay, analytical method, approved specification, batch documentation and traceability.
Have a supplier COA you are comparing? Send us the target assay and analytical method. KS Nutripharma can help identify the appropriate grade and qualification requirements for your project.
Cyanotis arachnoidea raw material → Extraction & concentration → Ecdysterone enrichment / standardization → Purification → Drying & milling → HPLC testing → Batch release
The processing route is adjusted according to the required Beta-Ecdysterone specification, including standard grades such as 50%, 60%, 95%, 98%, and 99% HPLC. Higher-assay grades may require additional purification and tighter process control than standard extract grades.
Typical Lead Time
For established Beta-Ecdysterone specifications and available production capacity, typical lead time is approximately 3–6 weeks from confirmed order and specification approval to batch release.
The actual lead time depends on:
- Required Beta-Ecdysterone assay
- Production quantity and batch planning
- Availability of Cyanotis arachnoidea raw material
- Extraction and purification requirements
- HPLC testing and specification verification
- Packaging and release requirements
Before production, the assay, test method, batch quantity, packaging specification, and COA requirements are confirmed to establish the applicable production schedule.
Each batch is released against the agreed specification before shipment. Depending on the required assay, processing and purification may affect powder appearance, bulk characteristics, achievable inclusion level, and cost per active dose.
Beta-Ecdysterone is supplied against an approved raw-material specification covering assay, identity, physical characteristics and applicable contaminant controls. The final QC panel depends on the selected grade, production specification and destination-market requirements.
| Parameter | Commercial Reference | Why It Matters |
|---|---|---|
| Beta-Ecdysterone assay | 50%, 60%, 95%, 98%, or 99% HPLC grades | Determines active concentration, formulation inclusion level and cost per active dose |
| Identity | Cyanotis arachnoidea / Beta-Ecdysterone (20-Hydroxyecdysone), CAS 5289-74-7 | Confirms the declared botanical source and target compound |
| Appearance | Grade-dependent powder appearance; higher-assay grades may be light yellow to off-white | Supports batch consistency and finished-product appearance assessment |
| Particle size | 80 mesh where specified | Influences blending, filling and dosage-form processing |
| Bulk density | Available against the approved specification / on request | Relevant to capsule fill volume and powder handling |
| Flowability | Evaluated according to manufacturing requirements | Affects filling and processing consistency |
| Loss on drying | According to approved raw-material specification | Relevant to storage stability and powder handling |
| Residue on ignition / sulfated ash | Controlled against the approved specification | Helps assess inorganic residue |
| Heavy metals | Lead, arsenic, cadmium and mercury according to specification | Supports contaminant control and destination-market requirements |
| Pesticides | According to applicable specification and destination market | Supports botanical raw-material qualification |
| Residual solvents | Where applicable | Confirms compliance with the approved specification |
| Microbiology | Applicable microbial limits, including relevant pathogen controls | Supports raw-material safety and manufacturing qualification |
Important: Not every parameter is necessarily tested on every batch unless it is included in the approved specification or required by the applicable testing program. Batch release is based on the agreed specification and applicable QC requirements.
The botanical source and agricultural practices can influence raw-material consistency. Learn more about our Cyanotis arachnoidea cultivation and GAP practices.
For commercial qualification, documentation supplied at KS Nutripharma allows buyers to verify the material specifications, batch identity, and applicable quality controls before production.
Typical Documentation
- Batch-specific Certificate of Analysis (COA)
- Approved product specification
- Analytical method information
- Sample documentation
- Heavy-metal and microbiological results where specified
- Packaging and storage information
- Supplier and lot traceability information
Key COA Items to Review
| COA Item | Why It Matters |
|---|---|
| Botanical identity | Confirms the declared Cyanotis arachnoidea source |
| Assay method | Shows how Beta-Ecdysterone content was measured, such as HPLC or an approved alternative method |
| Actual assay result | Allows formulation inclusion and active-dose calculations |
| Batch / lot number | Provides production and traceability control |
| Manufacturing date | Supports shelf-life and batch evaluation |
| Expiry / retest date | Supports inventory and procurement planning |
| Contaminant results | Helps verify compliance with specified heavy-metal, microbiological and other applicable limits |
For qualification, the sample COA should be compared with the specification and, where applicable, the documentation supplied for commercial production batches.
For commercial qualification, buyers can request a specification-matched sample and batch COA first. After the material is approved against the agreed specification, bulk production and delivery are scheduled according to the confirmed order requirements.
- Storage: Store in a cool, dry place away from direct sunlight according to the approved raw-material specification.
- Documented shelf life: 24 months under specified storage conditions.
- Retest: Apply retest requirements where specified by the approved specification.
KS Nutripharma supports beta-ecdysterone procurement with established manufacturing infrastructure, dedicated R&D resources and specification-based quality control. Our production platform is designed to support sample qualification, commercial batch production and repeat bulk supply for international B2B customers.
| Capability | KS Nutripharma |
| Manufacturing Experience | 19+ years |
| Facility | 81,000+ m² GMP-compliant facility |
| R&D | 2 dedicated R&D centers |
| Production Infrastructure | 12 automated production lines · 260+ professionals |
| Global Supply | 500+ brands · 60+ export markets |
| Quality Systems | GMP · ISO 9001 · ISO 22000 · HACCP · FSCC22000 |
| Supply Model | Sample → Qualification → Bulk Production → Repeat Supply |
| Documentation | Batch-specific COA · Product Specification · QC Documentation |
For beta-ecdysterone buyers, manufacturing capacity is only one part of supply assurance. We also align the commercial material with the approved assay, analytical method, QC requirements and destination-market documentation before repeat supply.
Request a Beta-Ecdysterone Sample & COA
Choose the procurement route that matches your current stage. You do not need to have every parameter finalized before contacting us.
Route A — Already Have a Specification
Send your specification, target assay, required analytical method and estimated quantity. We can confirm grade availability, review the applicable specification, provide a batch-specific COA for qualification and prepare a quotation.
Route B — Still Comparing Grades
Tell us your intended application, target assay and estimated volume. We can help identify the appropriate commercial specification and the documentation required for qualification.
| Information Needed | What to Provide |
| Target assay | Required beta-ecdysterone percentage and analytical method, if specified |
| Grade preference | HPLC (50%, 60%, 95%, 98%, 99%) or UV (90%, 95%) |
| Quantity | Bulk kilograms or agreed unit |
| Application | Supplement, sports nutrition or other specified use |
| Destination market | Country or region for regulatory and documentation assessment |
| COA requirements | Specific test panel or additional parameters |
| Sample need | Quantity and timeline for evaluation |
If you are developing a finished Beta-Ecdysterone supplement, explore our finished supplement manufacturing services.
Beta-Ecdysterone is available in 50%, 60%, 95%, 98%, and 99% HPLC grades, subject to the approved product specification and production availability. The appropriate grade depends on the target formulation, serving size, and required active concentration.
Our Beta-Ecdysterone is derived from Cyanotis arachnoidea. Botanical identity and the applicable raw-material specifications are confirmed as part of the qualification and batch-release process.
Assay is determined according to the approved analytical specification. For the listed standardized grades, HPLC is used as the primary assay reference. The applicable test method and specification should be confirmed before commercial production.
Yes. A representative sample and relevant documentation can be reviewed during raw-material qualification. Buyers can evaluate the material against the agreed specification before proceeding to commercial production.
Typical qualification documentation includes a batch-specific COA, product specification, analytical method information, and applicable heavy-metal, microbiological, pesticide, or residual-solvent documentation where required by the specification or destination market.
Lead time depends on the selected assay grade, order quantity, raw-material availability, production scheduling, testing requirements, and packaging specifications. The production schedule is confirmed after the grade, quantity, specification, and documentation requirements are finalized.
Yes. The appropriate assay grade depends on the target serving size, total formula weight, dosage form, and desired active loading. Higher-assay grades can be useful when the formula requires a lower raw-material inclusion level, while lower-assay grades may be more practical for higher-dose formulations. For finished-product development, see our Ecdysterone Supplement Manufacturing page.
Yes. The appropriate assay grade depends on the target serving size, total formula weight, dosage form, and desired active loading. Higher-assay grades can be useful when the formula requires a lower raw-material inclusion level, while lower-assay grades may be more practical for higher-dose formulations.
For brands developing a finished Beta-Ecdysterone product, see our Ecdysterone Supplement Manufacturing service page for capsule, tablet, powder, and other finished-product options.
